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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIN3A
All Species:
27.58
Human Site:
S274
Identified Species:
55.15
UniProt:
Q96ST3
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96ST3
NP_001138829.1
1273
145175
S274
P
P
L
P
P
Y
A
S
P
R
S
P
P
V
Q
Chimpanzee
Pan troglodytes
XP_510682
1273
145185
S274
P
P
L
P
P
Y
A
S
P
R
S
P
P
V
Q
Rhesus Macaque
Macaca mulatta
XP_001103539
1273
145217
S274
P
P
L
P
P
Y
A
S
P
R
S
P
P
V
Q
Dog
Lupus familis
XP_535546
1240
141674
S274
P
P
L
P
P
Y
A
S
P
R
S
P
P
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q60520
1282
146164
S274
P
P
L
P
P
Y
A
S
P
R
S
P
P
V
Q
Rat
Rattus norvegicus
NP_001102231
1129
127784
H214
Q
V
H
Q
I
P
T
H
G
I
Q
P
Q
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512119
1268
144524
S267
P
G
I
P
P
Y
A
S
P
R
S
P
P
V
Q
Chicken
Gallus gallus
XP_413695
1272
145279
S272
P
P
I
P
P
Y
A
S
P
R
S
P
P
V
Q
Frog
Xenopus laevis
NP_001081937
1275
145070
A275
P
S
P
R
S
P
P
A
Q
P
H
T
P
G
P
Zebra Danio
Brachydanio rerio
NP_001091650
1276
145765
A277
N
P
S
I
P
P
Y
A
S
P
R
S
P
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188916
1290
146297
S302
A
A
G
G
H
T
Y
S
Q
P
P
P
A
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22579
1536
174821
Q378
S
S
G
L
P
S
I
Q
Q
P
E
M
P
A
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.8
96.4
N.A.
97.4
86.8
N.A.
90.8
91.1
82.3
78
N.A.
N.A.
N.A.
N.A.
53
Protein Similarity:
100
99.9
99.8
96.9
N.A.
98.4
87.7
N.A.
94.9
94.9
89.5
86.9
N.A.
N.A.
N.A.
N.A.
67.5
P-Site Identity:
100
100
100
100
N.A.
100
13.3
N.A.
86.6
93.3
13.3
20
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
93.3
100
20
26.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
0
0
59
17
0
0
0
0
9
17
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
17
9
0
0
0
0
9
0
0
0
0
9
0
% G
% His:
0
0
9
0
9
0
0
9
0
0
9
0
0
0
9
% H
% Ile:
0
0
17
9
9
0
9
0
0
9
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
42
9
0
0
0
0
0
0
0
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
67
59
9
59
75
25
9
0
59
34
9
75
84
17
9
% P
% Gln:
9
0
0
9
0
0
0
9
25
0
9
0
9
0
67
% Q
% Arg:
0
0
0
9
0
0
0
0
0
59
9
0
0
0
0
% R
% Ser:
9
17
9
0
9
9
0
67
9
0
59
9
0
0
0
% S
% Thr:
0
0
0
0
0
9
9
0
0
0
0
9
0
0
0
% T
% Val:
0
9
0
0
0
0
0
0
0
0
0
0
0
59
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
59
17
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _